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SAAM Institute Inc saam ii software
Saam Ii Software, supplied by SAAM Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/saam+ii+software/saam+ii+software/us12296018-324-16-19
Average 90 stars, based on 1 article reviews
saam ii software - by Bioz Stars, 2026-09
90/100 stars

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Clinical Proteomics:

Article Title: Albumin binding peptide-drug (AlBiPeD) conjugates and methods of making and using same
Article Snippet: .. Plasma concentrations of Dox Equiv. of ABD-Dox versus time were fit to a two-compartment model using SAAM II software (SAAM Institute, Seattle, WA) and the elimination half-life and the area-under-curve were computed. ..

Article Title: Conjugate of Doxorubicin to Albumin-Binding Peptide Outperforms Aldoxorubicin.
Article Snippet: .. Plasma concentrations of Dox equiv. of ABD–Dox versus time were fit to a two-compartment model using SAAM II software (SAAM Institute, Seattle, WA) and the elimination half-life and the area under curve were computed. .. The tissue concentrations of Dox equiv. of ABD–Dox, AlDox, and free Dox at different time points were compared in GraphPad Prism software (GraphPad, San Diego, CA) by two-way ANOVA followed by Tukey– Kramer (Tukey’s) post-hoc test with P < 0.05 considered statistically significant.

Software:

Article Title: Albumin binding peptide-drug (AlBiPeD) conjugates and methods of making and using same
Article Snippet: .. Plasma concentrations of Dox Equiv. of ABD-Dox versus time were fit to a two-compartment model using SAAM II software (SAAM Institute, Seattle, WA) and the elimination half-life and the area-under-curve were computed. ..

Article Title: In vivo - in vitro correlation of antitumor activity of heat shock protein 90 (HSP90) inhibitors with a pharmacokinetics/pharmacodynamics analysis using NCI-N87 xenograft mice.
Article Snippet: The in vitro antitumor activity (e.g., IC50) of anticancer drugs is important for selecting candidate compounds for in vivo drug efficacy study in the early stage of drug discovery.. In this study, we investigated the relationship between in vitro IC50 and in vivo EC50 using six heat shock protein 90 (HSP90) inhibitors.. IC50 of each compound was calculated from in vitro cell proliferation assays using the NCI-N87 cancer cell line.

Article Title: Co-Targeting of BTK and TrxR as a Therapeutic Approach to the Treatment of Lymphoma
Article Snippet: .. The interaction factor (I) was determined using SAAM II software (SAAM Institute, Seattle, WA, USA), where I < 0, I = 0, and I > 0 indicated antagonistic, additive, and synergistic, respectively. ..

Article Title: Effects of replacing dietary monounsaturated fat with carbohydrate on HDL protein metabolism and proteome composition in humans
Article Snippet: .. Compartmental modeling Compartmental modeling was performed using SAAM II software (SAAM Institute, Seattle, Washington). ..

Article Title: Conjugate of Doxorubicin to Albumin-Binding Peptide Outperforms Aldoxorubicin.
Article Snippet: .. Plasma concentrations of Dox equiv. of ABD–Dox versus time were fit to a two-compartment model using SAAM II software (SAAM Institute, Seattle, WA) and the elimination half-life and the area under curve were computed. .. The tissue concentrations of Dox equiv. of ABD–Dox, AlDox, and free Dox at different time points were compared in GraphPad Prism software (GraphPad, San Diego, CA) by two-way ANOVA followed by Tukey– Kramer (Tukey’s) post-hoc test with P < 0.05 considered statistically significant.

Article Title: Effects of replacing dietary monounsaturated fat with carbohydrate on HDL protein metabolism and proteome composition in humans
Article Snippet: .. Compartmental modeling was performed using SAAM II software (SAAM Institute, Seattle, Washington). ..

other:

Article Title: Design, synthesis, and biological evaluation of novel diphenylamine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.
Article Snippet: A novel series of diphenylamine derivatives were designed and synthesized, and their biological activities were evaluated.. The anti-proliferative activities of the derivatives were tested against five human cancer cell lines (MCF-7, MDA-MB-231, A549, HeLa and HT29).. Among them, compound 5f exhibited the promising anti-proliferative activity against HT29 cell lines with the IC50 value of 23 nM.



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